HEALTH TESTING

AMTC HEALTH TESTING

ALL Breeders start as a Silver Breeder and may move up to Gold Breeder
upon completion of Health Testing and OFA Requirements.

The AMTC works with the following labs and organizations for genetic health disorders affecting canine companions:

GenSol Diagnostics ~ for disease clearance results.
Animal Genetics ~ for DNA profiling and disease clearance results.
ACCU-Viaguard ~ for DNA breed identification results.
Wisdom Health ~ Optimal Selection for DNA breed identification and disease clearance results.
Orthopedic Foundation for Animals (OFA) ~ for certifying canine body evaluation results. The American Morkshire Terrier Club, Inc., (AMTC) has the American Morkshire Terrier listed as a breed in the OFA database.

**When ordering tests and submission - you MUST use the breed's official name, American Morkshire Terrier**

OFA CERTIFICATION REQUIREMENTS

As a Gold Breeder, there are Health & OFA Certification requirements that must be completed for ALL AMTC Registered Breeding Dogs. OFA offers health clinics available to the public and you can visit OFA's list at: www.caninehealthclinics.org/ for a clinic in your area.

Genetic & OFA REQUIREments

The following are Genetic Health & OFA Certification's that are a required

PATELLA
CARDIAC
EYES
GENETIC TESTING
DNA VERIFICATION

Patellar Luxation Evaluation is classified by a veterinarian that examines your dog's patella or kneecap, part of the stifle joint (knee). In patellar luxation, the kneecap luxates (pops out) of place, either in a medial or lateral position. Patellar luxation fall into several categories:

Medial
Lateral
Luxation resulting from trauma

Numbers 1 & 2 are either known to be heritable or strongly suspected.
For the American Morkshire Terrier Club - OFA Evaluation is required at 1 Years (or Older) of Age - An OFA number will be issued to all dogs found to be normal at 12 months of age and older and a copy is to be submitted for ALL AMTC Gold Breeders.

Basic Cardiac Evaluation is classified by a veterinarian listening by (auscultation) with a stethoscope, and any cardiac murmurs or abnormal sounds should be referred to a veterinary cardiologist to perform a echocardiographic (echocardiogram) examination. Echocardiograms are to be performed by a veterinary cardiologist defined as, licensed veterinarian(s) with diplomate status in either the American College of Veterinary Medicine (ACVIM) or European College of Veterinary Medicine (ECVIM) cardiology. Cardiac evaluation fall into several categories:

Basic Cardiac Evaluation
Cardiac Murmur or Abnormal Sound
Echocardiographic Examination

Number 2 is either known to be heritable or strongly suspected.
For the American Morkshire Terrier Club - OFA Evaluation is required at 1 Years (or Older) of Age - An OFA number will be issued to all dogs found to be normal at 12 months of age and older and a copy is to be submitted for ALL AMTC Gold Breeders.

Eye Evaluation is a screening exam performed by a board certified veterinary ophthalmologist. The diagnosis obtained during an OFA exam refer only to the observable phenotype (clinical appearance) of an animal. This is why your dog be genetically tested to rule out any abnormal phenotype (genetic abnormalities). There are currently ten disorders for which there is an unequivocal recommendation against breeding in ALL breeds:

Keratoconjunctivitis
Cataract
Progressive Lens Luxation (PLL)
Glaucoma
Persistant Hyperplasic Primary Vitreous (PHPV)
Retinal Detachment
Retinal Dysplasia
Optic Nerve Coloboma
Optic Nerve Hypoplasia
Progressive Retinal Atrophy (PRA) - Progressive Rod-Cone Degeneration (PRCD)

Number 1-10 are either known to be heritable or strongly suspected.
For the American Morkshire Terrier Club - OFA Evaluation is required at 1 Years (or Older) of Age and recommended to repeat again at 3 Years (or Older) of Age - An OFA number will be issued to all dogs found to be normal at 12 months of age and older and must be normal upon repeat of examination a copy is to be submitted for ALL AMTC Gold Breeders.

Genetic Testing for dogs can help identify diseases and help owners to determine their dog's status for a genetic mutation in order to guide future breeding decisions. The three body systems most commonly affected across all breed dog populations are - Vision, Nervous, and Circulatory. The following breed susceptible genetic disease mutations seen in the American Morkshire Terrier, Maltese, Yorkshire Terrier and Biewer include:

Hyperuricosuria (HU)
Primary Lens Luxation (PLL)
Progressive Retinal Rod Cone Degeneration (PRA-prcd)
Degenerative Myelopathy (DM)

Numbers 1-3 are either known to be heritable or strongly suspected. Number 4 is not prevalent in the American Morkshire Terrier.
For the American Morkshire Terrier Club - Hyperuricosuria (HU), Primary Lens Luxation (PLL), and Progressive Retinal Rod-Cone Degeneration (PRA-prcd) - A Clear/Normal Result is issued to all dogs found to be normal and a copy is to be submitted for ALL AMTC Gold Breeders.

DNA Profiling Verification also known as "DNA fingerprinting" is a test that confirms the parentage of a litter. This test does not determine breed type. It identifies specific gene markers that are inherited by both parents:

ALL AMTC BREEDERS are required to submit a DNA Profile Verification on their breeding dogs within three years of joining AMTC.

For the American Morkshire Terrier Club - DNA Profiling Verification allows breeders, dog owners, and the AMTC to ensure that the AMTC Registry is accurate.

DNA Breed Verification also known as "DNA Breed Analysis" is a test that finds what dog breeds are found within a dog's unique DNA. This test does determine breed type. It identifies specific gene markers that genetically make up your dog's breed.

ALL American Morkshire Terrier's are recommended and will be required to have a DNA Breed Verification completed by January 30, 2027.
ALL Yorkshire Terrier's, Maltese, and Biewer's will be required to have a DNA Breed Verification completed after January 30, 2027 upon joining the American Morkshire Terrier Club that are not dual registered with a Registry the AMTC recognizes.

For the American Morkshire Terrier Club - DNA Breed Verification allows breeders, dog owners and the AMTC to ensure that the AMTC registers pure breed dogs.

If you have any questions regarding the above requirements you can email us at: info@amtcusa.com

AMTC APPROVED LABS FOR HEALTH CLEARANCE TESTING

*NOTE* If your dog has already been tested prior to July 15, 2019* - you can send those results to us by mail to: AMTC Registrar P.O. BOX 473, Burnsville, NC 28714. If not, you can obtain a DNA-profile Kit or DNA-verification test highlighted above under "order tests and submission."

Animal Genetic Testing and Research Lab
Department of Veterinary Science
108 Gluck Equine Research Center,
University of Kentucky
Lexington KY 40546-0099
Ph: 859-218-1193 Fax: 859-257-5169

Auburn University
Mary Boudreaux, DVM, PhD
Dept. of Pathobiology, College of Veterinary Medicine
166 Greene Hall
Auburn University, AL 36849
Ph: (334) 844-2692 Email: boudrmk@auburn.edu

Cornell University
Goldstein Molecular and Genetics Laboratory
Richard E. Goldstein, DVM, Dip ACVIM, Dip ECVIM-CA
Ph: 607-253-4480 Fax: 607-253-3534
E-mail: phpt@cornell.edu

Embark
186 Lincoln St., 6th Floor
Boston, MA 02111
E-mail: howdy@embarkvet.com

HealthGene
2175 Keele St.
Toronto, ON M6M 3Z4 Canada
Toll Free: 1-877-371-1551
Email: info@healthgene.co

Jefferson Medical College
Dept. of Neurology -Dr. David Wenger
1020 Locust St, 394
Philadelphia, PA 19107
Email: david.wenger@mail.tju.edu

Laboratory of Veterinary Genetics (LABGENVET)
University of Montreal
Faculty of Veterinary Medicine
David W. Silversides DVM, PhD.
3200 Sicotte, CP5000 St-Hyacinthe, Quebec, Canada J2S 7C6
Tel. 450-773-8521 x8464
David.w.silversides@umontreal.ca

Michigan State University
Laboratory of Comparative Medical Genetics
2209 Biomedical Physical Sciences
East Lansing, MI 48824

Laboratory of Canine Genetics and Molecular Medicine
567 Wilson Rd, BPS Bldg, MSU
East Lansing, MI 48824
Ph: (517) 884-5350

North Carolina State University
Veterinary Genetics Lab
1060 William Moore Drive RB 228
Raleigh, NC 27607
Ph: 919-513-3314 Email: vcgl@lists.ncsu.edu

NYU Medical Center – Neurogenetics Laboratory
Attn: Dr. Bai Jin Zeng NYU Medical Center
400 East 34th St. (Room RR210)
New York, NY 10016 Ph: 212-263-2943

OptiGen, LLC
Cornell Business & Technology Park
767 Warren Road, Suite 300
Ithaca, NY 14850
Ph: 607-257-0301 Fax: 607-257-0353
Email: genetest@optigen.com

Orivet Genetic Pet Care
20 Church Street
Mezzanine Level
Hartford, CT 06103
Ph: 860-952-3407
Email: USA@Orivet.com

Orthopedic Foundation for Animals
2300 E Nifong Boulevard
Columbia, Missouri, 65201-3806
Ph: (573) 442-0418 Fax: (573) 875-5073
Email: ofa@offa.org

Paw Prints Genetics
220 E Rowan, Suite 220
Spokane, WA 99207
Ph: 855-202-4889 Email: askus@pawprintgenetics.com

PennGEN Laboratories
3850 Spruce Street
Philadelphia, PA 19104-6010
Ph: (215) 898-3375

ProjectDog
636 San Pablo Ave
Albany, CA 94706
Ph: (510) 900-3899 Email: dogdna@projectdog.org

University of California – Davis Veterinary Genetics Laboratory
PO Box 1102
Davis, CA 95617-1102
Ph: (530) 752-2211

University of Minnesota – Canine Genetics Laboratory
College of Veterinary Medicine, University of Minnesota 295 AS/VM
1988 Fitch Ave
St. Paul, MN 55108
Ph: (612) 624-5322 Email: cgl@umn.edu

University of Missouri College of Vet Medicine
320 Connaway Hall
Columbia, MO 65211
Ph: (573) 884-3712 E-mail: HansenL@missouri.edu

University of Pennsylvania Section of Medical Genetics
School of Veterinary Medicine
Ryan Veterinary Hospital, Room 4018
3900 Delancey St.
Philadelphia, PA 19104
Ph: (215) 898-8076 Email: casalml@vet.upenn.edu

Veterinary Diagnostics Center (DDC)
225 Corporate Court
Fairfield, OH 45014
Toll-Free: (800) 625-0874 Email: contact@vetdnacenter.com

VetGen
3728 Plaza Drive, Suite One
Ann Arbor, MI 48108
Ph: 800-483-8436

VetNostic
www.vetnostic.com
Ph: (877) 255-9208

Washington State University–Veterinary Clinical Pharmacology Lab (WSU-VCPL)
PO Box 609
Pullman, WA 99163-0609
Ph: 509-335-3745 Fax: 509-335-6309
Email: VCPL@vetmed.wsu.edu

Wisdom Health
PO Box 87586
Vancouver, WA 98687
Toll Free: 1-888-K9 PET TEST (597-3883) Email: info@wisdomhealth.com